In his Talking Points Memo tonight, Bill O'Reilly reacted to a new NBC News/Wall Street Journal poll that shows Vice President Joe Biden beating the all the Republican presidential candidates in head-to-head match-ups.

O'Reilly pointed out that Biden has not entered the 2016 race yet. He added that the same poll found that 62 percent of people believe the nation is on the wrong track, while only 30 percent said the U.S. is headed in the right direction.

"The Factor" host said that Biden, as the vice president, endorses pretty much everything President Obama does, which has resulted in a poor economy and terrible foreign policy.

"So why would you vote for him?" O'Reilly wondered. "Talking Points believes the answer to that question is kind of cruel: Many Americans are simply dumb. They don't know what's going on, they don't pay attention, they don't care."

Watch the full Talking Points Memo and see Charles Krauthammer react in the clip above.

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