The family of an Arizona woman who vanished while hiking across a popular tourist trail in Spain is searching for answers.

Denise Thiem, 41, disappeared in April while hiking across the famed Camino de Santiago, a nearly 500-mile Catholic pilgrimage from France to Spain.

Thiem had recently quit her job to travel the world and was inspired to make the journey after watching the Martin Sheen movie “The Way," which focuses on a father's soul-searching journey on the trail.

Now, the FBI is working with Spanish national police to find her. 

The woman's brother, Cedric Thiem, told Greta Van Susteren tonight that he last spoke with his sister on April 20. 

He said that his sister was beginning a new chapter in her life and that she was "pretty excited about it. "

Watch the video above.