A massive explosion at a chemical plant in northern Spain has left a huge toxic orange cloud in the sky Thursday.

Jenna Lee reported on "Happening Now" that three people were injured in the blast, which was caused by two chemicals coming into contact during a delivery to the plant located in Igualada. 

Officials urged that residents in several towns nearby stay indoors and keep their windows closed.  

The plant is owned by Spanish company Simar. Roughly 65,000 people live in Igualada, which is located about 30 miles away from Barcelona. 

See the YouTube video below of a car driving closer to the toxic cloud.