Bill O’Reilly tonight called for the resignation of CDC Director Tom Frieden, who he said is not being forthcoming about the threat of Ebola.

“The Factor” host said it’s “very worrisome” that Nina Pham, a 26-year-old nurse who treated Thomas Eric Duncan, has been diagnosed with Ebola even though she was wearing protective gear.

O’Reilly reiterated that “there is no compelling reason why West Africans should be admitted to the USA” amid this epidemic, calling it a national security issue. He said that a new NBC News poll found that 58 percent also believe there should be a ban on flights from West African countries into the U.S.

O’Reilly’s team has asked Frieden a number of times to appear on “The Factor,” but O’Reilly said he won’t because he’s afraid.

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“He knows that I know he’s not being candid, that he is spinning the situation and not being forthcoming about how the disease is being spread. Frieden should resign.”

O’Reilly said that it is “stupid and irresponsible” to believe that civilian airport employees can spot Ebola that is dormant.

“It's a dumb and dangerous ruse, and Freiden is the chief propagandist,” he said.

O’Reilly said he’s just asking for common sense, which the Obama administration is rejecting. “But I will predict tonight, they will soon reverse course,” he said.

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“The Factor” host also touched on reports that U.S. bombing is not stopping the advance of ISIS.

“All of us who see things clearly knew that was going to be the case. I believe President Obama also knew that was going to be the case, but would not tell the American people,” O’Reilly said.

According to O’Reilly, Obama has created the myth that somehow, a 60-nation coalition – that is basically doing nothing – will defeat ISIS.

“The BS has to stop,” he said.

Watch the memo above.