The Houston Fire Department said that a motel fire that started Friday afternoon has left at least four firefighters injured. There are reportedly other firefighters now missing after a roof gave way at the site of the blaze.

Watch the latest video from the scene, above. Plus, get more details from the Associated Press: 

HOUSTON (AP) -- A five-alarm fire at a Houston motel has injured at least four firefighters.
The Houston Fire Department released a statement saying four firefighters have been taken to hospitals, though details about their injuries weren't provided.
The blaze broke out just after noon Friday at a restaurant and club at the Southwest Inn on U.S. 59, one of Houston's most heavily traveled expressways. Flames spread to the motel part of the building and were still shooting from the roof of the structure more than an hour later.
No cause for the blaze was immediately announced. Phone messages left with the fire department weren't immediately returned.
Temperatures in the low 90s and high humidity hampered firefighting efforts, and smoke from the fire snarled traffic on the expressway.