Academy Award-winning actor Philip Seymour Hoffman is dead at the age of 46 from an apparent drug overdose.

On Sunday, Hoffman’s body was discovered in his New York City apartment with heroin paraphernalia nearby. His drug addiction started as a teenager, but he had reportedly been sober for more than 20 years until he checked into rehab for heroin abuse last year.

Dr. Mehmet Oz joined Fox and Friends to talk about addiction. “Addictions in general are chronic, they’re fatal and they’re often incurable. The survival rates are very similar to having cancer.”

Heroin now is 40 times stronger than what was around 30 years ago. The drug is manufactured in countries like Mexico and Bolivia, making it impossible to predict how every dose will affect the body. In unmonitored settings, the side effect of slowing down the heart can often turn deadly. 

“The problem with heroin is it’s the most addictive of all drugs,” Dr. Oz explained. “It gives you a pure form of ecstasy.”

He said, “The big message for everyone out there watching is if you have a loved one who is addicted, you have to assume that they will always be addicted. Continuing to nudge them in the right direction is the only way to get them back.”