By FoxNews.com

Interior Secretary Ken Salazar will step down from his position in President Obama's Cabinet to spend time with his family on his ranch in Colorado, Fox News confirms.

The former U.S. senator plans to announce his resignation Wednesday, and is expected to stay on with the administration until the end of March.

Salazar was chosen to serve as interior secretary in 2008. His departure marks the latest in a series of high-profile resignations from the president's Cabinet.

Labor Secretary Hilda Solis, Treasury Secretary Tim Geithner, Secretary of State Hillary Clinton, and Defense Secretary Leon Panetta are among those leaving.